Worksheet
 
Yes  
 
Can't Determine  
 
No  
 
NA  
1. Would implementing the studied intervention or procedure (if found successful) result in improved outcomes for the patients/clients/population group? (Not Applicable for some epidemiological studies)
   
2. Did the authors study an outcome (dependent variable) or topic that the patients/clients/population group would care about?
 
3. Is the focus of the intervention or procedure (independent variable) or topic of study a common issue of concern to nutrition or dietetics practice?
 
4. Is the intervention or procedure feasible? (NA for some epidemiological studies)
   
1. Was the research question clearly stated?
 
2. Was the selection of study subjects/patients free from bias?
   
3. Were study groups comparable?
   
4. Was method of handling withdrawals described?
     
5. Was blinding used to prevent introduction of bias?
     
6. Were intervention/therapeutic regimens/exposure factor or procedure and any comparison(s) described in detail? Were interveningfactors described?
   
7. Were outcomes clearly defined and the measurements valid and reliable?
   
8. Was the statistical analysis appropriate for the study design and type of outcome indicators?
 
9. Are conclusions supported by results with biases and limitations taken into consideration?
 
10. Is bias due to study’s funding or sponsorship unlikely?
 
 
Research Design and Implementation: Primary Research
  Augustin et al 2004 Bertuccio et al 2009 Cust et al 2007 Flood et al. 2006 George et al 2009 Giles et al 2006 Heinen et al 2008 Howarth et al 2008 Johnson et al 2005 Kabat et al 2008 Lajous et al 2005 Lajous et al 2008 Larsson et al 2006 Larsson et al 2007 Am J Epidemiol Larsson et al 2007 Int J Cancer McCann SE, McCann WE et al, 2007 McCarl M, Harnack L et al, 2006 Michaud DS, Fuchs CS et al, 2005 Nothlings U, Murphy SP et al, 2007 Patel AV, McCullough ML et al, 2007 Randi G, Ferraroni M et al, 2008 Sieri S, Pala V et al, 2007 Silvera SA, Jain M et al, 2005 Silvera SA, Jain M et al, 2007 Silvera SA, Rohan TE et al, 2005 (endometrial) Silvera SA, Rohan TE et al, 2005 (pancreatic) Strayer L, Jacobs DR Jr et al, 2007 Weijenberg MP, Mullie PF et al, 2008
Overall Quality Rating Neutral Positive Positive Positive Positive Neutral Neutral Neutral Neutral Neutral Neutral Neutral Neutral Neutral Neutral Positive Neutral Positive Neutral Positive Neutral Neutral Positive Positive Neutral Positive Positive Neutral
Relevance Questions
1. Would implementing the studied intervention or procedure (if found successful) result in improved outcomes for the patients/clients/population group? (Not Applicable for some epidemiological studies)
N/A
 
N/A
 
N/A
 
Yes
 
N/A
 
N/A
 
N/A
 
N/A
 
N/A
 
N/A
 
N/A
 
N/A
 
Yes
 
Yes
 
Yes
 
Yes
 
N/A
 
N/A
 
N/A
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
2. Did the authors study an outcome (dependent variable) or topic that the patients/clients/population group would care about?
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
3. Is the focus of the intervention or procedure (independent variable) or topic of study a common issue of concern to nutrition or dietetics practice?
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
4. Is the intervention or procedure feasible? (NA for some epidemiological studies)
N/A
 
Yes
 
N/A
 
Yes
 
N/A
 
N/A
 
N/A
 
N/A
 
N/A
 
N/A
 
N/A
 
N/A
 
Yes
 
Yes
 
Yes
 
Yes
 
N/A
 
N/A
 
N/A
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
 
Validity Questions
1. Was the research question clearly stated?
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
2. Was the selection of study subjects/patients free from bias?
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
No
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
No
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
3. Were study groups comparable?
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
No
 
Yes
 
Yes
 
No
 
4. Was method of handling withdrawals described?
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
No
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
N/A
 
5. Was blinding used to prevent introduction of bias?
Yes
 
Yes
 
N/A
 
N/A
 
N/A
 
Yes
 
N/A
 
Yes
 
N/A
 
Yes
 
Yes
 
N/A
 
Yes
 
Yes
 
Yes
 
Yes
 
N/A
 
N/A
 
N/A
 
???
 
Yes
 
N/A
 
N/A
 
Yes
 
Yes
 
Yes
 
Yes
 
N/A
 
6. Were intervention/therapeutic regimens/exposure factor or procedure and any comparison(s) described in detail? Were interveningfactors described?
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
N/A
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
7. Were outcomes clearly defined and the measurements valid and reliable?
No
 
Yes
 
Yes
 
Yes
 
Yes
 
No
 
Yes
 
No
 
No
 
No
 
No
 
No
 
No
 
No
 
No
 
Yes
 
No
 
Yes
 
No
 
Yes
 
No
 
No
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
8. Was the statistical analysis appropriate for the study design and type of outcome indicators?
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
9. Are conclusions supported by results with biases and limitations taken into consideration?
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
10. Is bias due to study’s funding or sponsorship unlikely?
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes
 
Yes