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What effect does folic acid supplementation (with or without additional B vitamin supplementation) have on risk of stroke among persons with or without pre-existing vascular disease? (DGAC 2010)

Conclusion

Evidence that folic acid supplementation might prevent stroke is limited due to inconsistency, with  the most recent meta-analysis documenting no benefit.

Grade

Limited
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Evidence Summaries

What is the evidence that supports this conclusion? For more information, click on the Evidence Summary link below.
 
What effect does folic acid supplementation (with or without additional B vitamin supplementation) have on risk of stroke among persons with or without pre-existing vascular disease?